I think 5 months is one of the easier times to travel with a baby! Try to keep baby sucking (nursing, a bottle, or a pacifier) during takeoff and landing. A baby carrier like a sling or soft carrier might be handy during the flight, to give your arms a break (especially while walking the aisles if you need to stretch your legs and/or bounce baby a little bit). Bring a TON of extra diapers and spare clothes for BOTH of you in your carry-on bags. Ditto lots of little trash bags to contain trash and soiled things in case of spit-up or worse. ;)
Have a great trip! When do you travel?